Halophilic and halotolerant microorganisms: bio-factories of amazing compounds with an outstanding biotechnological potential
Keywords:
Halophilic microorganisms - halotolerant microorganisms - bioactive compounds - biotechnological applications.Abstract
Introduction: Halophilic and halotolerant microorganisms are a group of extremophiles that are adapted to survive in high salt conditions. The successful occupancy of life form in such unfavorable environment has attracted and focused the attention of the scientific community for potential applications of their bioactive molecules. This mini-review summarizes some potential applications of those microorganisms in biotechnology that have been highlighted in specialty journals with a significant impact factor.
Methods: To carry out this exploratory review involve the online survey including and coordinating information from convincing publications on in vitro works by means of electronic database and scientific tools such as Google Scholar, PubMed, Springer link and Science Direct.
Results: This systematic review was structured based on the years of the publication of the journals, the categories and the used keywords. The results showed the potential of production of highly stable biomolecules by halophilic and halotolerant such as extreme-enzymes, antimicrobial compounds, antioxidant, biomolecules with anticancer and anti-diabetic activities, compatible solutes, carotenoid pigments, exo-polysaccharides, and biosurfactants products which can be used in medicine, agriculture, bioenergy and other industries and that can resolve current challenges.
Conclusion: Halophiles and halotolerant microorganisms have the potential to offer significant opportunities for biotechnology. Their high metabolic diversity and highly stable biomolecules suggests that they will prove even more valuable in the future.
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