In vitro antioxidant and antidiabetic activities of the hydro-acetone extracts of Ricinus communis and Teucrium polium from Tlemcen area
DOI:
https://doi.org/10.46325/jnpra.v3i02.64Keywords:
Ricinus communis; Teucrium polium; total polyphenol contents; DPPH; FRAP; α-amylase.Abstract
The aim of the present study was to determine total phenolic and total flavonoid contents in hydro-acetone extracts from the roots of Ricinus communis and the aerial part of Teucrium polium, and to determine in vitro their antioxidant and antidiabetic activities using DPPH, FRAP, and α-amylase activity assay, respectively. The obtained results reveled that R. communis roots hydro-acetone extract contains high contents of polyphenols (499.55 ± 0.02 µg GAE/mg DE) and flavonoids (28.21 ± 0.01 µg Cat eq/mg DE) than T. polium aerial part extracts. Both plant extracts showed in vitro antioxidant and antidiabetic activities, where R. communis showed a potent free radical scavenging activity (DPPH IC50=2.01 ± 0.01 µg/mL) and high iron reduction capacity (FRAP EC50=41.32 ± 0.01 µg/mL) more than T. polium extract (DPPH IC50= 7.40 ± 0.01 µg/mL; FRAP EC50=74.63 ± 0.01 µg/mL). In addition, in α-amylase activity assay T. polium was more efficient in inhibiting this enzyme (EC50= 924 ± 0.19 µg/mL) compared to R. communis extract (EC50= 1300 ± 0.03 µg/mL).
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